MyBioSource.com's Tim3 antibody (allophycocyanin) is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry.
Description
Mouse monoclonal Tim3 antibody (allophycocyanin)
This F38-2E2 monoclonal antibody reacts with human T cell immunoglobulin and mucin domain-containing molecule -3. The cell surface receptor is expressed on activated CD4+ T cell subsets, CD8+ T cells, monocytes, dendritic cells, and mast cells. Due to alternative splicing, TIM-3 exists as membrane-bound and soluble forms. Galectin-9 has been identified as the ligand for TIM-3. In humans, this receptor negatively regulates CD4+ T cells, influencing the secretion of some Th1- and Th-17-related cytokines. TIM-3 has also been implicated in tolerance, autoimmune disease, and HIV infection